Welcome to the 4th Circular & Self-Amplifying RNA Therapeutics Summit
Unleashing the Next Generation of RNAs for Widespread Therapeutic Applications
With CSL Seqirus and Arcturus Therapeutics successfully developing the first approved self-amplifying RNA vaccine, the field of next generation RNAs celebrates the potential of circular and self-amplifying RNAs to provide improved stability, durability, longevity and efficacy for treating a wide array of diseases.
This May, the 4th Circular & Self-Amplifying RNA Therapeutics Summit is landing back in Boston, as the unique opportunity to unite with leading stakeholders in the next generation RNA field, including the likes of Sail Biomedicines, Merck, Novo Nordisk, Replicate Bioscience and more. This is your one-stop shop to hear the latest approaches and applications of circular and self-amplifying RNA therapeutics and vaccines and gain actionable insights for fast-tracking your RNA programs towards the clinic.
Join 80+ RNA experts navigating through challenges such as RNA design, delivery, purity and manufacturing to accelerate high-quality and scalable next generation RNA therapeutics and vaccines towards approval and the patients in need.
What's New for 2025

Brand New Speaker Faculty & Exclusive Data
With over 80% new speakers from key stakeholders, hear brand-new data and insights from the likes of CSL Seqirus, Merck & Co, Sail Biomedicines, RiboX Therapeutics, VLP Therapeutics and more, gain insights into promise of circular and self-amplifying RNA for providing more durable, stable and potent therapeutics and vaccines.

Addressing Circular & Self-Amplifying RNA Bottlenecks
As an event-dedicated to the next generation RNA community, we're excited to provide you with deep dive workshops, data-driven presentations and interactive discussion addressing challenges in manufacturing, purification, optimal application, analysis and more to help you advance RNA therapies towards approval.

Improving Next Generation RNA Investment
During an interactive fireside chat with MPM Capital and Orbital Therapeutics, hear what innovations are needed to spark greater investment in the circular and self-amplifying RNA field. This session will highlight priority actions and applications for driving more success in the next generation RNA field.
Speaker Faculty
Discover our 17+ expert speakers covering all things Circular & Self-Amplifying RNA



Michael
Mingueneau
Head, Immunology
Sail Biomedicines
Erik Digman
Wiklund
Chief Executive Officer
Circio
Gilles Besin
Chief Scientific
Officer
Orbital
Therapeutics



Fei Liu
Associate Director,
Molecular Biology
CSL Seqirus
Nichole Lareau
Associate Principal
Scientist
Merck & Co
Amit Khandhar
Director, Formulations
HDT Bio



“Circular RNA represents an innovative modality that offers several advantages over linear RNA. I believe that attending the meeting will provide an excellent opportunity for me to share insights and learn more about this promising form of RNA”
Gilles Besin, Chief Scientific Officer

“I look forward to connecting with like-minded industry and academic peers working to advance the saRNA vaccines and therapeutics into the clinic”
Amit Khandhar, Director, Formulations
