Deep-Dive Workshop: Accomplishing Improved Encapsulation & Targeting of RNA Therapeutics by Uncovering Innovative Delivery Strategies for More Potent & Effective Therapies
Time: 11:00 am
day: Conference Day Two
Details:
A major bottleneck inhibiting the full potential of all RNA therapeutics is delivery. With self-amplifying and circular RNA payloads typically being larger than those of linear mRNA, this complicates their encapsulation. Furthermore, while current lipid nanoparticles (LNPs) have demonstrated safety and efficacy of mRNA vaccines, their use has been restricted to intramuscular administration. During this workshop, we will discuss the limitations of current delivery technologies and how alternative delivery strategies may enhance RNA stability, improve tolerability and optimize targeting precision for safe and tissue-specific delivery.
This session will deep dive into:
- Exploring alternative technologies for efficient RNA delivery and targeted tissue engagement
- Investigating the potential of LNPs and alternate technologies for targeted delivery of circular and self-amplifying RNA therapeutics
- Discuss critical quality attributes that drive safe and effective delivery technologies
